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Endothelial overexpression of endothelin-1 modulates aortic, carotid, iliac and renal arterial responses in obese mice

Endothelin-1 (ET-1) is essential for mammalian development and life, but it has also been implicated in increased cardiovascular risk under pathophysiological conditions. The aim of this study was to determine the impact of endothelial overexpression of the prepro-endothelin-1 gene on endothelium-de...

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Pubblicato in:Acta Pharmacol Sin
Autori principali: Baretella, Oliver, Chung, Sookja K, Xu, Aimin, Vanhoutte, Paul M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386308/
https://ncbi.nlm.nih.gov/pubmed/28216625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.138
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