Disruption of SorCS2 reveals differences in the regulation of stereociliary bundle formation between hair cell types in the inner ear

Behavioural anomalies suggesting an inner ear disorder were observed in a colony of transgenic mice. Affected animals were profoundly deaf. Severe hair bundle defects were identified in all outer and inner hair cells (OHC, IHC) in the cochlea and in hair cells of vestibular macular organs, but hair...

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Detaylı Bibliyografya
Yayımlandı:PLoS Genet
Asıl Yazarlar: Forge, Andrew, Taylor, Ruth R., Dawson, Sally J., Lovett, Michael, Jagger, Daniel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386298/
https://ncbi.nlm.nih.gov/pubmed/28346477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006692
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