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SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton

Formin proteins are key regulators of the cytoskeleton involved in developmental and homeostatic programs, and human disease. For these reasons, small molecules interfering with Formins’ activity have gained increasing attention. Among them, small molecule inhibitor of Formin Homology 2 domains (SMI...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Isogai, Tadamoto, van der Kammen, Rob, Innocenti, Metello
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386218/
https://ncbi.nlm.nih.gov/pubmed/25925024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09802
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