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Analysis of Translational Initiation in Coxsackievirus B3 Suggests an Alternative Explanation for the High Frequency of R(+4) in the Eukaryotic Consensus Motif

Translational initiation of most eukaryotic mRNAs occurs when a preinitiation complex binds to the 5′ cap, scans the mRNA, and selects a particular AUG codon as the initiation site. Selection of the correct initiation codon relies, in part, on its flanking residues; in mammalian cells, the core of t...

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Main Authors: Harkins, Stephanie, Cornell, Christopher T., Whitton, J. Lindsay
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC538586/
https://ncbi.nlm.nih.gov/pubmed/15613327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.987-996.2005
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