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Deletions within the 5′UTR of coxsackievirus B3: consequences for virus translation and replication

Key features of an ideal RNA-based vaccine against coxsackievirus B3 (CVB3) are (i) limited genome replication/virus production (to minimize vaccine-related pathology) and (ii) abundant virus protein synthesis (to maximize immunogenicity). These attributes may apply to CVB3 RNAs lacking up to 250 nu...

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Hlavní autoři: Hunziker, Isabelle P., Cornell, Christopher T., Whitton, J. Lindsay
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2190293/
https://ncbi.nlm.nih.gov/pubmed/17084431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.09.041
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