The t(10;14)(q24;q11) of T-cell acute lymphoblastic leukemia juxtaposes the delta T-cell receptor with TCL3, a conserved and activated locus at 10q24.

We cloned the t(10;14) recurrent translocation from CD3-negative T-cell acute lymphoblastic leukemia cells. The breakpoint at 14q11 involved an intermediate rearrangement of the delta T-cell receptor locus, suggesting that the translocation arose at the time of antigen receptor assemblage. Transloca...

Descripció completa

Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Zutter, M, Hockett, R D, Roberts, C W, McGuire, E A, Bloomstone, J, Morton, C C, Deaven, L L, Crist, W M, Carroll, A J, Korsmeyer, S J
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1990
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53854/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2326274/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.8.3161
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!