Anti-Human Immunodeficiency Virus Type 1 (HIV-1) Antibodies 2F5 and 4E10 Require Surprisingly Few Crucial Residues in the Membrane-Proximal External Region of Glycoprotein gp41 To Neutralize HIV-1

The conserved membrane-proximal external region (MPER) of human immunodeficiency virus type 1 (HIV-1) gp41 is a target of two broadly neutralizing human monoclonal antibodies, 2F5 and 4E10, and is an important lead for vaccine design. However, immunogens that bear MPER epitopes so far have not elici...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Zwick, Michael B., Jensen, Richard, Church, Sarah, Wang, Meng, Stiegler, Gabriela, Kunert, Renate, Katinger, Hermann, Burton, Dennis R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538539/
https://ncbi.nlm.nih.gov/pubmed/15613352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1252-1261.2005
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker