Antigenicity and Immunogenicity of a Synthetic Human Immunodeficiency Virus Type 1 Group M Consensus Envelope Glycoprotein

Genetic variation of human immunodeficiency virus (HIV-1) represents a major obstacle for AIDS vaccine development. To decrease the genetic distances between candidate immunogens and field virus strains, we have designed and synthesized an artificial group M consensus env gene (CON6 gene) to be equi...

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Main Authors: Gao, Feng, Weaver, Eric A., Lu, Zhongjing, Li, Yingying, Liao, Hua-Xin, Ma, Benjiang, Alam, S. Munir, Scearce, Richard M., Sutherland, Laura L., Yu, Jae-Sung, Decker, Julie M., Shaw, George M., Montefiori, David C., Korber, Bette T., Hahn, Beatrice H., Haynes, Barton F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC538535/
https://ncbi.nlm.nih.gov/pubmed/15613343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.2.1154-1163.2005
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