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Inducible Turnover of Optineurin Regulates T Cell Activation
Optineurin (Optn) is an adaptor protein with homology to NF-κB essential-modulator (NEMO), the regulatory subunit of the IκB kinase (IKK) complex. Dysregulation of Optn has been linked to neurodegenerative, autoimmune and bone diseases. Optn shares a high degree of homology with NEMO, but is not par...
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| Publicado no: | Mol Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5385146/ https://ncbi.nlm.nih.gov/pubmed/28192730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2017.01.027 |
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