Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients

The biologic plausibility of an association between type 2 diabetes mellitus (T2D) and lung cancer has received increasing attention, but the results of investigations remain largely inconclusive. In the present study we investigated the influence of the anti-diabetic drug metformin on the cytotoxic...

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Publicado en:Neoplasia
Autores principales: Xiao, Zhiguang, Gaertner, Silvia, Morresi-Hauf, Alicia, Genzel, Rebecca, Duell, Thomas, Ullrich, Axel, Knyazev, Pjotr G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press 2017
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Original article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384889/
https://ncbi.nlm.nih.gov/pubmed/28391030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.02.011
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