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A strategy to identify linker-based modules for the allosteric regulation of antibody-antigen binding affinities of different scFvs

Antibody single-chain variable fragments (scFvs) are used in a variety of applications, such as for research, diagnosis and therapy. Essential for these applications is the extraordinary specificity, selectivity and affinity of antibody paratopes, which can also be used for efficient protein purific...

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Pubblicato in:MAbs
Autori principali: Kellmann, Sarah-Jane, Dübel, Stefan, Thie, Holger
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384732/
https://ncbi.nlm.nih.gov/pubmed/28055297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2016.1277302
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