Enhancement of antibody functions through Fc multiplications

Antibodies carry out a plethora of functions through their crystallizable fragment (Fc) regions, which can be naturally tuned by the adoption of several isotypes and post-translational modifications. Protein engineering enables further Fc function modulations through modifications of the interaction...

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Veröffentlicht in:MAbs
Hauptverfasser: Wang, Qun, Chen, Yan, Pelletier, Mark, Cvitkovic, Romana, Bonnell, Jessica, Chang, Chien-Ying, Koksal, Adem C., O'Connor, Ellen, Gao, Xizhe, Yu, Xiang-Qing, Wu, Herren, Stover, C. Kendall, Dall'Acqua, William F., Xiao, Xiaodong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2017
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Reports
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384704/
https://ncbi.nlm.nih.gov/pubmed/28102754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1281505
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