Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

PURPOSE: A microdose drug–drug interaction (DDI) study may be a valuable tool for anticipating drug interaction at therapeutic doses. This study aimed to compare the magnitude of DDIs at microdoses and regular doses to explore the applicability of a microdose DDI study. PATIENTS AND METHODS: Six hea...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Drug Des Devel Ther
Prif Awduron: Park, Gab-jin, Bae, Soo Hyeon, Park, Wan-Su, Han, Seunghoon, Park, Min-Ho, Shin, Seok-Ho, Shin, Young G, Yim, Dong-Seok
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Dove Medical Press 2017
Pynciau:
Clinical Trial Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384691/
https://ncbi.nlm.nih.gov/pubmed/28408803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S131797
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