Effect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy mice

Renal tubular epithelial-to-mesenchymal transition (EMT) and renal tubular interstitial fibrosis are the main pathological changes of diabetic nephropathy (DN), which is a common cause of end-stage renal disease. Previous studies have suggested that berberine (BBR) has antifibrotic effects in the ki...

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Bibliografische gegevens
Gepubliceerd in:Drug Des Devel Ther
Hoofdauteurs: Yang, Guannan, Zhao, Zongjiang, Zhang, Xinxue, Wu, Amin, Huang, Yawei, Miao, Yonghui, Yang, Meijuan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Dove Medical Press 2017
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384688/
https://ncbi.nlm.nih.gov/pubmed/28408805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S124971
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