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IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo

NK cells have shown promise in therapy of hematological cancers, in particular against acute myeloid leukemia. In contrast, the more NK cell-resistant acute lymphoblastic leukemia (ALL) is difficult to treat with NK-cell-based therapies, and we hypothesized that pre-activation of NK cells could over...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Boieri, Margherita, Ulvmoen, Aina, Sudworth, Amanda, Lendrem, Clare, Collin, Matthew, Dickinson, Anne M., Kveberg, Lise, Inngjerdingen, Marit
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384344/
https://ncbi.nlm.nih.gov/pubmed/28405496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1274478
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