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Cerebrospinal fluid biomarkers for Alzheimer's disease in Down syndrome

Down syndrome (DS), present in nearly six million people, is associated with an extremely high risk to develop Alzheimer's disease (AD). Amyloid-β and tau pathology are omnipresent from age 40 years onward, but clinical symptoms do not appear in all DS individuals. Dementia diagnostics is compl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Alzheimers Dement (Amst)
Hauptverfasser: Dekker, Alain D., Fortea, Juan, Blesa, Rafael, De Deyn, Peter P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384293/
https://ncbi.nlm.nih.gov/pubmed/28413821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2017.02.006
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