Secreted Effectors Encoded Within and Outside of the Francisella Pathogenicity Island Promote Intramacrophage Growth

The intracellular bacterial pathogen Francisella tularensis causes tularemia, a zoonosis that can be fatal. The type VI secretion system (T6SS) encoded by the Francisella pathogenicity island (FPI) is critical for the virulence of this organism. Existing studies suggest that the complete repertoire...

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Publicado en:Cell Host Microbe
Autores principales: Eshraghi, Aria, Kim, Jungyun, Walls, Alexandra C., Ledvina, Hannah E., Miller, Cheryl, Ramsey, Kathryn M., Whitney, John C., Radey, Matthew C., Peterson, S. Brook, Ruhland, Brittany R., Tran, Bao Q., Goo, Young Ah, Goodlett, David R., Dove, Simon L., Celli, Jean, Veesler, David, Mougous, Joseph D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384264/
https://ncbi.nlm.nih.gov/pubmed/27832588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.10.008
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