Secreted Effectors Encoded Within and Outside of the Francisella Pathogenicity Island Promote Intramacrophage Growth

The intracellular bacterial pathogen Francisella tularensis causes tularemia, a zoonosis that can be fatal. The type VI secretion system (T6SS) encoded by the Francisella pathogenicity island (FPI) is critical for the virulence of this organism. Existing studies suggest that the complete repertoire...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Eshraghi, Aria, Kim, Jungyun, Walls, Alexandra C., Ledvina, Hannah E., Miller, Cheryl, Ramsey, Kathryn M., Whitney, John C., Radey, Matthew C., Peterson, S. Brook, Ruhland, Brittany R., Tran, Bao Q., Goo, Young Ah, Goodlett, David R., Dove, Simon L., Celli, Jean, Veesler, David, Mougous, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384264/
https://ncbi.nlm.nih.gov/pubmed/27832588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.10.008
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