Secreted Effectors Encoded Within and Outside of the Francisella Pathogenicity Island Promote Intramacrophage Growth

The intracellular bacterial pathogen Francisella tularensis causes tularemia, a zoonosis that can be fatal. The type VI secretion system (T6SS) encoded by the Francisella pathogenicity island (FPI) is critical for the virulence of this organism. Existing studies suggest that the complete repertoire...

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Publié dans:Cell Host Microbe
Auteurs principaux: Eshraghi, Aria, Kim, Jungyun, Walls, Alexandra C., Ledvina, Hannah E., Miller, Cheryl, Ramsey, Kathryn M., Whitney, John C., Radey, Matthew C., Peterson, S. Brook, Ruhland, Brittany R., Tran, Bao Q., Goo, Young Ah, Goodlett, David R., Dove, Simon L., Celli, Jean, Veesler, David, Mougous, Joseph D.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5384264/
https://ncbi.nlm.nih.gov/pubmed/27832588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.10.008
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