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‘Hints' in the killer protein gasdermin D: unveiling the secrets of gasdermins driving cell death
Pyroptosis is a lytic form of cell death distinguished from apoptosis, ferroptosis, necrosis, necroptosis, NETosis, oncosis, pyronecrosis and autophagy. Proinflammatory caspases cleave a gasdermin D (GSDMD) protein to generate a 31 kDa N-terminal domain. The cleavage relieves the intramolecular inhi...
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| Publicado no: | Cell Death Differ |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5384029/ https://ncbi.nlm.nih.gov/pubmed/28362726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.24 |
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