Host cell-derived lactate functions as an effector molecule in Neisseria meningitidis microcolony dispersal

The development of meningococcal disease, caused by the human pathogen Neisseria meningitidis, is preceded by the colonization of the epithelial layer in the nasopharynx. After initial adhesion to host cells meningococci form aggregates, through pilus-pilus interactions, termed microcolonies from wh...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Sigurlásdóttir, Sara, Engman, Jakob, Eriksson, Olaspers Sara, Saroj, Sunil D., Zguna, Nadezda, Lloris-Garcerá, Pilar, Ilag, Leopold L., Jonsson, Ann-Beth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383330/
https://ncbi.nlm.nih.gov/pubmed/28384279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006251
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