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Host cell-derived lactate functions as an effector molecule in Neisseria meningitidis microcolony dispersal.

The development of meningococcal disease, caused by the human pathogen Neisseria meningitidis, is preceded by the colonization of the epithelial layer in the nasopharynx. After initial adhesion to host cells meningococci form aggregates, through pilus-pilus interactions, termed microcolonies from wh...

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Bibliographische Detailangaben
Hauptverfasser: Sara Sigurlásdóttir, Jakob Engman, Olaspers Sara Eriksson, Sunil D Saroj, Nadezda Zguna, Pilar Lloris-Garcerá, Leopold L Ilag, Ann-Beth Jonsson
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2017-04-01
Schriftenreihe:PLoS Pathogens
Online Zugang:http://europepmc.org/articles/PMC5383330?pdf=render
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