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Host cell-derived lactate functions as an effector molecule in Neisseria meningitidis microcolony dispersal.

The development of meningococcal disease, caused by the human pathogen Neisseria meningitidis, is preceded by the colonization of the epithelial layer in the nasopharynx. After initial adhesion to host cells meningococci form aggregates, through pilus-pilus interactions, termed microcolonies from wh...

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Main Authors: Sara Sigurlásdóttir, Jakob Engman, Olaspers Sara Eriksson, Sunil D Saroj, Nadezda Zguna, Pilar Lloris-Garcerá, Leopold L Ilag, Ann-Beth Jonsson
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science (PLoS) 2017-04-01
Series:PLoS Pathogens
Acceso en liña:http://europepmc.org/articles/PMC5383330?pdf=render
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