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Internalization of tau antibody and pathological tau protein detected with a flow cytometry multiplexing approach

INTRODUCTION: Tau immunotherapy has emerged as a promising approach to clear tau aggregates from the brain. Our previous findings suggest that tau antibodies may act outside and within neurons to promote such clearance. METHODS: We have developed an approach using flow cytometry, a human neuroblasto...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Shamir, Dov B., Rosenqvist, Nina, Rasool, Suhail, Pedersen, Jan T., Sigurdsson, Einar M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383206/
https://ncbi.nlm.nih.gov/pubmed/27016263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2016.01.013
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