Mutation effects predicted from sequence co-variation

Increasing interest in determining the effects of genetic variation for bioengineering, human health and basic biological research has propelled the development of technologies for high-throughput mutagenesis and selection. However, since designing functional assays is challenging and systematic tes...

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Bibliographic Details
Published in:Nat Biotechnol
Main Authors: Hopf, Thomas A., Ingraham, John B., Poelwijk, Frank J., Schärfe, Charlotta P.I., Springer, Michael, Sander, Chris, Marks, Debora S.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5383098/
https://ncbi.nlm.nih.gov/pubmed/28092658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3769
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