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Carboxyethylpyrroles: From Hypothesis to the Discovery of Biologically Active Natural Products

Our research on the roles of lipid oxidation in human disease is guided by chemical intuition. For example, we postulated that 2-(ω-carboxyethyl)pyrrole (CEP) derivatives of primary amines would be produced through covalent adduction of a γ-hydroxyalkenal generated, in turn, through oxidative fragme...

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Detaylı Bibliyografya
Yayımlandı:Chem Res Toxicol
Yazar: Salomon, Robert G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382959/
https://ncbi.nlm.nih.gov/pubmed/27750413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.6b00304
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