Prioritisation of structural variant calls in cancer genomes

Sensitivity of short read DNA-sequencing for gene fusion detection is improving, but is hampered by the significant amount of noise composed of uninteresting or false positive hits in the data. In this paper we describe a tiered prioritisation approach to extract high impact gene fusion events from...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:PeerJ
Hoofdauteurs: Ahdesmäki, Miika J., Chapman, Brad A., Cingolani, Pablo, Hofmann, Oliver, Sidoruk, Aleksandr, Lai, Zhongwu, Zakharov, Gennadii, Rodichenko, Mikhail, Alperovich, Mikhail, Jenkins, David, Carr, T. Hedley, Stetson, Daniel, Dougherty, Brian, Barrett, J. Carl, Johnson, Justin H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: PeerJ Inc. 2017
Onderwerpen:
Bioinformatics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382922/
https://ncbi.nlm.nih.gov/pubmed/28392986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.3166
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items