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Disambiguate: An open-source application for disambiguating two species in next generation sequencing data from grafted samples

Grafting of cell lines and primary tumours is a crucial step in the drug development process between cell line studies and clinical trials. Disambiguate is a program for computationally separating the sequencing reads of two species derived from grafted samples. Disambiguate operates on DNA or RNA-s...

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Bibliografiske detaljer
Udgivet i:F1000Res
Main Authors: Ahdesmäki, Miika J., Gray, Simon R., Johnson, Justin H., Lai, Zhongwu
Format: Artigo
Sprog:Inglês
Udgivet: F1000Research 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130069/
https://ncbi.nlm.nih.gov/pubmed/27990269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.10082.2
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