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Cytosolic co-delivery of miRNA-34a and docetaxel with core-shell nanocarriers via caveolae-mediated pathway for the treatment of metastatic breast cancer

Co-delivery of microRNAs and chemotherapeutic drugs into tumor cells is an attractive strategy for synergetic breast cancer therapy due to their complementary mechanisms. In this work, a core-shell nanocarrier coated by cationic albumin was developed to simultaneously deliver miRNA-34a and docetaxel...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Li, Yang, Xin, Lv, Yaqi, Xin, Xiaofei, Qin, Chao, Han, Xiaopeng, Yang, Lei, He, Wei, Yin, Lifang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382875/
https://ncbi.nlm.nih.gov/pubmed/28383524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46186
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