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Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK

BACKGROUND: Programmed cell death of motoneurons in the developing spinal cord is thought to be regulated through the availability of target-derived neurotrophic factors. When deprived of trophic support, embryonic spinal motoneurons in vitro over-express FasL, a ligand activating a Fas-mediated dea...

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Bibliographic Details
Main Authors: Barthélémy, Catherine, Henderson, Christopher E, Pettmann, Brigitte
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC538283/
https://ncbi.nlm.nih.gov/pubmed/15569384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-5-48
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