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Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK
BACKGROUND: Programmed cell death of motoneurons in the developing spinal cord is thought to be regulated through the availability of target-derived neurotrophic factors. When deprived of trophic support, embryonic spinal motoneurons in vitro over-express FasL, a ligand activating a Fas-mediated dea...
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Auteurs principaux: | , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
BioMed Central
2004
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC538283/ https://ncbi.nlm.nih.gov/pubmed/15569384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-5-48 |
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