Repeated low-dose kainate administration in C57BL/6J mice produces temporal lobe epilepsy pathology but infrequent spontaneous seizures

More efficient or translationally relevant approaches are needed to model acquired temporal lobe epilepsy (TLE) in genetically tractable mice. The high costs associated with breeding and maintaining transgenic, knock-in, or knock-out lines places a high value on the efficiency of induction and anima...

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Bibliographische Detailangaben
Veröffentlicht in:Exp Neurol
Hauptverfasser: Umpierre, Anthony D., Bennett, Isaiah V., Nebeker, Lismore D., Newell, Thomas G., Tian, Bruce B., Thomson, Kyle E., White, H. Steve, White, John A., Wilcox, Karen S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382800/
https://ncbi.nlm.nih.gov/pubmed/26896834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2016.02.014
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