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GRASP1 regulates synaptic plasticity and learning through endosomal recycling of AMPA receptors

Learning depends on experience-dependent modification of synaptic efficacy and neuronal connectivity in the brain. We provide direct evidence for physiological roles of the recycling endosome protein GRASP1 in glutamatergic synapse function and animal behavior. Mice lacking GRASP1 showed abnormal ex...

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Dades bibliogràfiques
Publicat a:Neuron
Autors principals: Chiu, Shu-Ling, Diering, Graham Hugh, Ye, Bing, Takamiya, Kogo, Chen, Chih-Ming, Jiang, Yuwu, Niranjan, Tejasvi, Schwartz, Charles E., Wang, Tao, Huganir, Richard L.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382714/
https://ncbi.nlm.nih.gov/pubmed/28285821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.02.031
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