GRASP1 regulates synaptic plasticity and learning through endosomal recycling of AMPA receptors

Learning depends on experience-dependent modification of synaptic efficacy and neuronal connectivity in the brain. We provide direct evidence for physiological roles of the recycling endosome protein GRASP1 in glutamatergic synapse function and animal behavior. Mice lacking GRASP1 showed abnormal ex...

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Udgivet i:Neuron
Main Authors: Chiu, Shu-Ling, Diering, Graham Hugh, Ye, Bing, Takamiya, Kogo, Chen, Chih-Ming, Jiang, Yuwu, Niranjan, Tejasvi, Schwartz, Charles E., Wang, Tao, Huganir, Richard L.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382714/
https://ncbi.nlm.nih.gov/pubmed/28285821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.02.031
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