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Next-generation sequencing enables the discovery of more diverse positive clones from a phage-displayed antibody library

Phage display technology provides a powerful tool to screen a library for a binding molecule via an enrichment process. It has been adopted as a critical technology in the development of therapeutic antibodies. However, a major drawback of phage display technology is that because the degree of the e...

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Dettagli Bibliografici
Pubblicato in:Exp Mol Med
Autori principali: Yang, Wonjun, Yoon, Aerin, Lee, Sanghoon, Kim, Soohyun, Han, Jungwon, Chung, Junho
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382563/
https://ncbi.nlm.nih.gov/pubmed/28336957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.22
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