Preclinical development of a humanized neutralizing antibody targeting HGF

Hepatocyte growth factor (HGF) and its receptor, cMET, play critical roles in cell proliferation, angiogenesis and invasion in a wide variety of cancers. We therefore examined the anti-tumor activity of the humanized monoclonal anti-HGF antibody, YYB-101, in nude mice bearing human glioblastoma xeno...

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Publicado en:Exp Mol Med
Autores principales: Kim, Hyori, Hong, Sung Hee, Kim, Jung Yong, Kim, In-Chull, Park, Young-Whan, Lee, Song-Jae, Song, Seong-Won, Kim, Jung Ju, Park, Gunwoo, Kim, Tae Min, Kim, Yun-Hee, Park, Jong Bae, Chung, Junho, Kim, In-Hoo
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382562/
https://ncbi.nlm.nih.gov/pubmed/28336956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.21
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