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Substituent Effects on the pH Sensitivity of Acetals and Ketals and Their Correlation with Encapsulation Stability in Polymeric Nanogels

Effect of structural variations in acetal- and ketal- based linkers upon their degradation kinetics is studied through the design, synthesis and study of six series of molecules, comprising a total of eighteen different molecules. Through this systematic study, we show that the structural fine-tunin...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Liu, Bin, Thayumanavan, S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382500/
https://ncbi.nlm.nih.gov/pubmed/28106385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11181
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