Molecular basis of differential resistance to cycloguanil and pyrimethamine in Plasmodium falciparum malaria.

Proguanil and pyrimethamine are antifolate drugs with distinct chemical structures that are used commonly in the prophylaxis and treatment of Plasmodium falciparum malaria. Clinical reports and field studies have suggested that some parasites refractory to proguanil can be treated with pyrimethamine...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Peterson, D S, Milhous, W K, Wellems, T E
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1990
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53825/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2183222/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.8.3018
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