Interaction between prenatal pesticide exposure and a common polymorphism in the PON1 gene on DNA methylation in genes associated with cardio-metabolic disease risk—an exploratory study

BACKGROUND: Prenatal environmental conditions may influence disease risk in later life. We previously found a gene-environment interaction between the paraoxonase 1 (PON1) Q192R genotype and prenatal pesticide exposure leading to an adverse cardio-metabolic risk profile at school age. However, the m...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Declerck, Ken, Remy, Sylvie, Wohlfahrt-Veje, Christine, Main, Katharina M., Van Camp, Guy, Schoeters, Greet, Vanden Berghe, Wim, Andersen, Helle R.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382380/
https://ncbi.nlm.nih.gov/pubmed/28396702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0336-4
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