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Paraoxonase 1 Polymorphism and Prenatal Pesticide Exposure Associated with Adverse Cardiovascular Risk Profiles at School Age

BACKGROUND: Prenatal environmental factors might influence the risk of developing cardiovascular disease later in life. The HDL-associated enzyme paraoxonase 1 (PON1) has anti-oxidative functions that may protect against atherosclerosis. It also hydrolyzes many substrates, including organophosphate...

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Detalhes bibliográficos
Main Authors: Andersen, Helle R., Wohlfahrt-Veje, Christine, Dalgård, Christine, Christiansen, Lene, Main, Katharina M., Nellemann, Christine, Murata, Katsuyuki, Jensen, Tina K., Skakkebæk, Niels E., Grandjean, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352943/
https://ncbi.nlm.nih.gov/pubmed/22615820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036830
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