Extinct type of human parvovirus B19 persists in tonsillar B cells

Parvovirus B19 (B19V) DNA persists lifelong in human tissues, but the cell type harbouring it remains unclear. We here explore B19V DNA distribution in B, T and monocyte cell lineages of recently excised tonsillar tissues from 77 individuals with an age range of 2–69 years. We show that B19V DNA is...

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Udgivet i:Nat Commun
Main Authors: Pyöriä, Lari, Toppinen, Mari, Mäntylä, Elina, Hedman, Lea, Aaltonen, Leena-Maija, Vihinen-Ranta, Maija, Ilmarinen, Taru, Söderlund-Venermo, Maria, Hedman, Klaus, Perdomo, Maria F.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382274/
https://ncbi.nlm.nih.gov/pubmed/28374737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14930
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