Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging

Cognitive decline is a major biomedical challenge as the global population ages. Elevated levels of the longevity factor klotho suppress aging, enhance cognition, and promote synaptic plasticity and neural resilience against aging and Alzheimer’s disease (AD)-related pathogenic proteins. Here, we ex...

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書目詳細資料
發表在:Brain Imaging Behav
Main Authors: Yokoyama, Jennifer S., Marx, Gabe, Brown, Jesse A., Bonham, Luke W., Wang, Dan, Coppola, Giovanni, Seeley, William W., Rosen, Howard J., Miller, Bruce L., Kramer, Joel H., Dubal, Dena B.
格式: Artigo
語言:Inglês
出版: Springer US 2016
主題:
SI: Resilience/Reserve in AD
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382127/
https://ncbi.nlm.nih.gov/pubmed/27714549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11682-016-9598-2
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