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The Role of Microglia in Inherited White-Matter Disorders and Connections to Frontotemporal Dementia

Microglia play a critical but poorly understood role in promoting white-matter homeostasis. In this review, we leverage advances in human genetics and mouse models of leukodystrophies to delineate our current knowledge and identify outstanding questions regarding the impact of microglia on central n...

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Detalhes bibliográficos
Publicado no:Appl Clin Genet
Main Authors: Sirkis, Daniel W, Bonham, Luke W, Yokoyama, Jennifer S
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8020808/
https://ncbi.nlm.nih.gov/pubmed/33833548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S245029
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