Diphtheria toxin and its ADP-ribosyltransferase-defective homologue CRM197 possess deoxyribonuclease activity.

The cytotoxic mechanism of diphtheria toxin (DTx) is associated with its ability to inhibit protein synthesis by ADP-ribosylation of elongation factor 2. Although DTx intoxication leads to internucleosomal DNA cleavage and cell lysis, these events do not occur when protein synthesis is inhibited by...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Bruce, C, Baldwin, R L, Lessnick, S L, Wisnieski, B J
Format: Artigo
Sprog:Inglês
Udgivet: 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC53820/
https://ncbi.nlm.nih.gov/pubmed/2109323
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker