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The abundance of the ARL2 GTPase and its GAP, ELMOD2, at mitochondria are modulated by the fusogenic activity of mitofusins and stressors

Mitochondria are essential, dynamic organelles that respond to a number of stressors with changes in morphology that are linked to several mitochondrial functions, though the mechanisms involved are poorly understood. We show that the levels of the regulatory GTPase ARL2 and its GAP, ELMOD2, are spe...

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Publicat a:PLoS One
Autors principals: Newman, Laura E., Schiavon, Cara R., Zhou, Chengjing, Kahn, Richard A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381910/
https://ncbi.nlm.nih.gov/pubmed/28380071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175164
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