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Non-invasive phenotyping and drug testing in single cardiomyocytes or beta-cells by calcium imaging and optogenetics

Identification of drug induced electrical instability of the heart curtails development, and introduction, of potentially proarrhythmic drugs. This problem usually requires complimentary contact based approaches such as patch-clamp electrophysiology combined with field stimulation electrodes to obse...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Chang, Yu-Fen, Broyles, Connor N., Brook, Frances A., Davies, Mark J., Turtle, Cameron W., Nagai, Takeharu, Daniels, Matthew J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381843/
https://ncbi.nlm.nih.gov/pubmed/28379974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174181
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