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Development of cancer vaccines targeting brachyury, a transcription factor associated with tumor EMT

The epithelial-mesenchymal transition (EMT) is recognized as a relevant process during the progression of carcinomas towards metastatic disease. Epithelial cancer cells undergoing an EMT program may acquire mesenchymal features, motility, invasiveness and resistance to a variety of anti-cancer thera...

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Detalhes bibliográficos
Publicado no:Cells Tissues Organs
Main Authors: Hamilton, Duane H., David, Justin M., Dominguez, Charli, Palena, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381518/
https://ncbi.nlm.nih.gov/pubmed/28214895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000446495
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