The T-box transcription factor Brachyury promotes epithelial-mesenchymal transition in human tumor cells

Metastatic disease is responsible for the majority of human cancer deaths. Understanding the molecular mechanisms of metastasis is a major step in designing effective cancer therapeutics. Here we show that the T-box transcription factor Brachyury induces in tumor cells epithelial-mesenchymal transit...

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Detalhes bibliográficos
Main Authors: Fernando, Romaine I., Litzinger, Mary, Trono, Paola, Hamilton, Duane H., Schlom, Jeffrey, Palena, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810072/
https://ncbi.nlm.nih.gov/pubmed/20071775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38379
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