Brachyury, a driver of the epithelial-mesenchymal transition, is overexpressed in human lung tumors: an opportunity for novel interventions against lung cancer

PURPOSE: The epithelial-mesenchymal transition (EMT) is emerging as a critical factor for the progression and metastasis of carcinomas, as well as drug resistance. The T-box transcription factor Brachyury has been recently characterized as a driver of EMT in human carcinoma cells. The purpose of thi...

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Detalhes bibliográficos
Main Authors: Roselli, Mario, Fernando, Romaine I., Guadagni, Fiorella, Spila, Antonella, Alessandroni, Jhessica, Palmirotta, Raffaele, Costarelli, Leopoldo, Litzinger, Mary, Hamilton, Duane, Huang, Bruce, Tucker, Joanne, Tsang, Kwong-Yok, Schlom, Jeffrey, Palena, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472640/
https://ncbi.nlm.nih.gov/pubmed/22611028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3211
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