Overexpression of the EMT Driver Brachyury in Breast Carcinomas: Association With Poor Prognosis

BACKGROUND: The epithelial–mesenchymal transition (EMT) has been implicated as an important process in tumor cell invasion, metastasis, and drug resistance. The transcription factor brachyury has recently been described as a driver of EMT of human carcinoma cells. METHODS: Brachyury mRNA and protein...

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Publicado en:J Natl Cancer Inst
Autores principales: Palena, Claudia, Roselli, Mario, Litzinger, Mary T., Ferroni, Patrizia, Costarelli, Leopoldo, Spila, Antonella, Cavaliere, Francesco, Huang, Bruce, Fernando, Romaine I., Hamilton, Duane H., Jochems, Caroline, Tsang, Kwong-Yok, Cheng, Qing, Lyerly, H. Kim, Schlom, Jeffrey, Guadagni, Fiorella
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568990/
https://ncbi.nlm.nih.gov/pubmed/24815864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju054
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