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Repression of CIITA by the Epstein–Barr virus transcription factor Zta is independent of its dimerization and DNA binding

Repression of the cellular CIITA gene is part of the immune evasion strategy of the γherpes virus Epstein–Barr virus (EBV) during its lytic replication cycle in B-cells. In part, this is mediated through downregulation of MHC class II gene expression via the targeted repression of CIITA, the cellula...

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Dades bibliogràfiques
Publicat a:J Gen Virol
Autors principals: Balan, Nicolae, Osborn, Kay, Sinclair, Alison J.
Format: Artigo
Idioma:Inglês
Publicat: Microbiology Society 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381392/
https://ncbi.nlm.nih.gov/pubmed/26653871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000369
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