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Repression of CIITA by the Epstein–Barr virus transcription factor Zta is independent of its dimerization and DNA binding

Repression of the cellular CIITA gene is part of the immune evasion strategy of the γherpes virus Epstein–Barr virus (EBV) during its lytic replication cycle in B-cells. In part, this is mediated through downregulation of MHC class II gene expression via the targeted repression of CIITA, the cellula...

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Detaylı Bibliyografya
Yayımlandı:J Gen Virol
Asıl Yazarlar: Balan, Nicolae, Osborn, Kay, Sinclair, Alison J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Microbiology Society 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5381392/
https://ncbi.nlm.nih.gov/pubmed/26653871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.000369
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