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The complement system in age-related macular degeneration: A review of rare genetic variants and implications for personalized treatment

Age-related macular degeneration (AMD) is a progressive retinal disease and the major cause of irreversible vision loss in the elderly. Numerous studies have found both common and rare genetic variants in the complement pathway to play a role in the pathogenesis of AMD. In this review we provide an...

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Detalhes bibliográficos
Publicado no:Mol Immunol
Main Authors: Geerlings, Maartje J., de Jong, Eiko K., den Hollander, Anneke I.
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5380947/
https://ncbi.nlm.nih.gov/pubmed/27939104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2016.11.016
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