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Highly Penetrant Alleles in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a complex disease caused by a combination of genetic and environmental factors. Genome-wide association studies have identified several common genetic variants associated with AMD, which together account for 15%–65% of the heritability of AMD. Multiple hypot...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Perspect Med
Main Authors: den Hollander, Anneke I., de Jong, Eiko K.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355254/
https://ncbi.nlm.nih.gov/pubmed/25377141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a017202
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